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- • Intermediate-sized cancers require individual decision making about the most appropriate treatment. Factors
- such as the site, stage, degree of lymph node involvement and general status of the patient will influence the
- type of therapy chosen.
- • Second primaries have been reported in up to a quarter of these patients.
- • Most recurrences occur in the first two to three years, and close follow-up is essential so that cure may still be
- possible. Examinations as well as previously abnormal staging studies are repeated to document the progress of
- treatment or detect recurrence.
- • Because of other illnesses related to smoking and alcohol use, many patients die from illnesses other than the
- cancer.
- • Small localized superficial cancers can be successfully treated with radiotherapy alone, surgery alone or laser
- excision . Radiation tends to be used first to try to preserve the voice. There are also some surgical procedures
- for small cancers that preserve the voice.
- • Recent studies of patients with advanced laryngeal cancer suggest a role for chemotherapy before radiotherapy
- in an attempt to preserve the larynx.
- • Advanced cancers are often treated by a combination of surgery and radiotherapy. Because the cure rate is low,
- consideration should be given to clinical trials evaluating chemotherapy, hyperfractionated (several doses a
- day) radiotherapy, radiation sensitizers or particle beam radiotherapy.
-